Ionic Channels in the Therapy of Malignant Glioma

Glioma is among the deadliest tumors worldwide. Despite its relative low onset incidence, glioma, especially malignant glioma, causes high mortality. Due to the utmost aggressiveness of tumor cells, malignant glioma is almost incurable by conventional therapeutic approaches. Finding new molecular targets, which are responsible for tumor progression, can amplify our understanding about malignant glioma and targeting these molecules combining with conventional approaches may ameliorate the therapeutic outcome for patients with malignant glioma.